Complete nucleotide sequence of an attenuated hepatitis A virus: comparison with wild-type virus.

The complete nucleotide sequence of an attenuated hepatitis A virus, HAV HM-175/7 MK-5, was determined from cloned cDNA. This virus was derived from wild-type HAV HM-175 after 32 passages in African green monkey kidney cells. The resultant cell culture-adapted virus is attenuated for chimpanzees. Th...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Cohen, J I, Rosenblum, B, Ticehurst, J R, Daemer, R J, Feinstone, S M, Purcell, R H
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1987
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304679/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3031686/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2497
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