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Mechanism of the t(14;18) chromosomal translocation: structural analysis of both derivative 14 and 18 reciprocal partners.

To elucidate the mechanism of the t(14;18)(q32;q21) chromosomal translocation found in follicular lymphoma, we examined the structure of both derivative (der) chromosomal breakpoints as well as their germ-line predecessors. We noted that chromosome segment 18q21 was juxtaposed with immunoglobulin he...

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Библиографические подробности
Опубликовано в::Proc Natl Acad Sci U S A
Главные авторы: Bakhshi, A, Wright, J J, Graninger, W, Seto, M, Owens, J, Cossman, J, Jensen, J P, Goldman, P, Korsmeyer, S J
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1987
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304658/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3104914/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2396
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