Mechanism of the t(14;18) chromosomal translocation: structural analysis of both derivative 14 and 18 reciprocal partners.

To elucidate the mechanism of the t(14;18)(q32;q21) chromosomal translocation found in follicular lymphoma, we examined the structure of both derivative (der) chromosomal breakpoints as well as their germ-line predecessors. We noted that chromosome segment 18q21 was juxtaposed with immunoglobulin he...

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Autori principali: Bakhshi, A, Wright, J J, Graninger, W, Seto, M, Owens, J, Cossman, J, Jensen, J P, Goldman, P, Korsmeyer, S J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1987
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC304658/
https://ncbi.nlm.nih.gov/pubmed/3104914
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