RFX1 regulates CD70 and CD11a expression in lupus T cells by recruiting the histone methyltransferase SUV39H1

INTRODUCTION: Regulatory factor X-box 1 (RFX1) can interact with DNA methyltransferase 1 (DNMT1) and histone deacetylase 1 (HDAC1), and RFX1 down-regulation contributes to DNA hypomethylation and histone H3 hyperacetylation at the cluster of differentiation (CD) 11a and CD70 promoters in CD4(+ )T ce...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhao, Ming, Wu, Xiaoyan, Zhang, Qing, Luo, Shuangyan, Liang, Gongping, Su, Yuwen, Tan, Yixin, Lu, Qianjin
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046540/
https://ncbi.nlm.nih.gov/pubmed/21192791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3214
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