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Loss of heterozygosity in human ductal breast tumors indicates a recessive mutation on chromosome 13.

The genotypes at chromosomal loci defined by recombinant DNA probes revealing restriction fragment length polymorphisms were determined in constitutional and tumor tissue from 10 cases of ductal breast cancer: eight premenopausal females and two males. Somatic loss of constitutional heterozygosity w...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Lundberg, C, Skoog, L, Cavenee, W K, Nordenskjöld, M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1987
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304653/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3031679/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2372
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