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Loss of heterozygosity in human ductal breast tumors indicates a recessive mutation on chromosome 13.

The genotypes at chromosomal loci defined by recombinant DNA probes revealing restriction fragment length polymorphisms were determined in constitutional and tumor tissue from 10 cases of ductal breast cancer: eight premenopausal females and two males. Somatic loss of constitutional heterozygosity w...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Lundberg, C, Skoog, L, Cavenee, W K, Nordenskjöld, M
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1987
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304653/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3031679/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2372
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