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Pre-analytic variables and phospho-specific antibodies: the Achilles heel of immunohistochemistry

Immunohistochemistry is the most common method for companion diagnostic testing in breast cancer. The readings for estrogen receptor, progesterone receptor, and Her2 directly affect prescription of critical therapies. However, immunohistochemistry is highly sensitive to innumerable pre-analytic vari...

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Detalhes bibliográficos
Main Authors: Siddiqui, Summar, Rimm, David L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046444/
https://ncbi.nlm.nih.gov/pubmed/21176180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2782
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