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Pre-analytic variables and phospho-specific antibodies: the Achilles heel of immunohistochemistry

Immunohistochemistry is the most common method for companion diagnostic testing in breast cancer. The readings for estrogen receptor, progesterone receptor, and Her2 directly affect prescription of critical therapies. However, immunohistochemistry is highly sensitive to innumerable pre-analytic vari...

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Autors principals: Siddiqui, Summar, Rimm, David L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046444/
https://ncbi.nlm.nih.gov/pubmed/21176180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2782
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