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Pre-analytic variables and phospho-specific antibodies: the Achilles heel of immunohistochemistry

Immunohistochemistry is the most common method for companion diagnostic testing in breast cancer. The readings for estrogen receptor, progesterone receptor, and Her2 directly affect prescription of critical therapies. However, immunohistochemistry is highly sensitive to innumerable pre-analytic vari...

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Autori principali: Siddiqui, Summar, Rimm, David L
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046444/
https://ncbi.nlm.nih.gov/pubmed/21176180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2782
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