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Transforming Growth Factor β Neutralization within Cardiac Allografts by Decorin Gene Transfer Attenuates Chronic Rejection
Chronic allograft rejection (CR) is the leading cause of late graft failure following organ transplantation. CR is a progressive disease, characterized by deteriorating graft function, interstitial fibrosis, cardiac hypertrophy and occlusive neointima development. TGFβ, known for its immunosuppressi...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046403/ https://ncbi.nlm.nih.gov/pubmed/19917705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902736 |
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