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Expression of the stem cell marker ALDH1 in BRCA1 related breast cancer

INTRODUCTION: The BRCA1 protein makes mammary stem cells differentiate into mature luminal and myoepithelial cells. If a BRCA1 mutation results in a differentiation block, an enlarged stem cell component might be present in the benign tissue of BRCA1 mutation carriers, and these mammary stem cells c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Heerma van Voss, Marise R., van der Groep, Petra, Bart, Joost, van der Wall, Elsken, van Diest, Paul J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046359/
https://ncbi.nlm.nih.gov/pubmed/21336637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-010-0007-3
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