A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions

Abnormal accumulation of α-synuclein is associated with several neurodegenerative disorders (synucleinopathies), including sporadic Parkinson’s disease (PD). Genetic mutations and multiplication of α-synuclein cause familial forms of PD and polymorphisms in the α-synuclein gene are associated with P...

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Main Authors: Fleming, Sheila M., Mulligan, Caitlin K., Richter, Franziska, Mortazavi, Farzad, Lemesre, Vincent, Frias, Carmen, Zhu, Chunni, Stewart, Alistair, Gozes, Illana, Morimoto, Bruce, Chesselet, Marie-Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046337/
https://ncbi.nlm.nih.gov/pubmed/21193046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2010.12.011
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