Mutations in the 2-microns circle site-specific recombinase that abolish recombination without affecting substrate recognition.
The site-specific recombinase encoded by the yeast plasmid 2-microns circle (FLP) forms a transient covalent linkage with its substrate DNA via a tyrosine residue, which appears to be located near its COOH terminus. The homology of the COOH terminus of FLP with that of the Int family of recombinases...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1987
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304614/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3104911/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2189 |
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