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Mutations in the 2-microns circle site-specific recombinase that abolish recombination without affecting substrate recognition.

The site-specific recombinase encoded by the yeast plasmid 2-microns circle (FLP) forms a transient covalent linkage with its substrate DNA via a tyrosine residue, which appears to be located near its COOH terminus. The homology of the COOH terminus of FLP with that of the Int family of recombinases...

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Bibliografiske detaljer
Main Authors: Prasad, P V, Young, L J, Jayaram, M
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC304614/
https://ncbi.nlm.nih.gov/pubmed/3104911
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