Mutations in the 2-microns circle site-specific recombinase that abolish recombination without affecting substrate recognition.

The site-specific recombinase encoded by the yeast plasmid 2-microns circle (FLP) forms a transient covalent linkage with its substrate DNA via a tyrosine residue, which appears to be located near its COOH terminus. The homology of the COOH terminus of FLP with that of the Int family of recombinases...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Prasad, P V, Young, L J, Jayaram, M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304614/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3104911/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2189
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