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Cigarette Smoke-Related Hydroquinone Dysregulates MCP-1, VEGF and PEDF Expression in Retinal Pigment Epithelium in Vitro and in Vivo

BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of legal blindness in the elderly population. Debris (termed drusen) below the retinal pigment epithelium (RPE) have been recognized as a risk factor for dry AMD and its progression to wet AMD, which is characterized by choroida...

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Detalhes bibliográficos
Main Authors: Pons, Marianne, Marin-Castaño, Maria E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046136/
https://ncbi.nlm.nih.gov/pubmed/21386905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016722
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