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Central administration of insulin-like growth factor-I decreases depressive-like behavior and brain cytokine expression in mice

Exogenous administration of insulin-like growth factor (IGF)-I has anti-depressant properties in rodent models of depression. However, nothing is known about the anti-depressant properties of IGF-I during inflammation, nor have mechanisms by which IGF-I alters behavior following activation of the in...

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Autori principali: Park, Sook-Eun, Dantzer, Robert, Kelley, Keith W, McCusker, Robert H
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045937/
https://ncbi.nlm.nih.gov/pubmed/21306618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-12
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