Enzymatic analysis of the effect of naturally occurring Leu138Pro mutation identified in SHV β-lactamase on hydrolysis of penicillin and ampicillin

BACKGROUND: The aim of this study was to analyze the significance of leucine to proline substitution at position 138(Leu138Pro) on the hydrolysis of penicillin and ampicillin that we identified in the bla(SHV )gene of clinical Escherichia coli swine isolate. RESULTS: Kinetic analysis of the mutant p...

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Detalhes bibliográficos
Main Authors: Rayamajhi, Nabin, Joo, Jeong Chan, Cha, Seung Bin, Pokherl, Subarna, Shin, Min Kyung, Yoo, Young Je, Yoo, Han Sang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045869/
https://ncbi.nlm.nih.gov/pubmed/21291571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-11-29
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