LRRK2 Kinase Regulates Synaptic Morphology through Distinct Substrates at the Presynaptic and Postsynaptic Compartments of the Drosophila Neuromuscular Junction

Mutations in leucine-rich repeat kinase 2 (LRRK2) are linked to familial as well as sporadic forms of Parkinson's disease (PD), a neurodegenerative disease characterized by dysfunction and degeneration of dopaminergic and other types of neurons. The molecular and cellular mechanisms underlying...

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Bibliographic Details
Main Authors: Lee, Seongsoo, Liu, Hsin-Ping, Lin, Wei-Yong, Guo, Huifu, Lu, Bingwei
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045823/
https://ncbi.nlm.nih.gov/pubmed/21159966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1807-10.2010
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