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LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction

Parkinson's disease gene leucine-rich repeat kinase 2 (LRRK2) has been implicated in a number of processes including the regulation of mitochondrial function, autophagy and endocytic dynamics; nevertheless, we know little about its potential role in the regulation of synaptic plasticity. Here w...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Penney, Jay, Tsurudome, Kazuya, Liao, Edward H., Kauwe, Grant, Gray, Lindsay, Yanagiya, Akiko, R. Calderon, Mario, Sonenberg, Nahum, Haghighi, A. Pejmun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960312/
https://ncbi.nlm.nih.gov/pubmed/27432119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12188
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