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A machine learning approach for genome-wide prediction of morbid and druggable human genes based on systems-level data

BACKGROUND: The genome-wide identification of both morbid genes, i.e., those genes whose mutations cause hereditary human diseases, and druggable genes, i.e., genes coding for proteins whose modulation by small molecules elicits phenotypic effects, requires experimental approaches that are time-cons...

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Detalhes bibliográficos
Main Authors: Costa, Pedro R, Acencio, Marcio L, Lemke, Ney
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045802/
https://ncbi.nlm.nih.gov/pubmed/21210975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-S5-S9
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