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A machine learning approach for genome-wide prediction of morbid and druggable human genes based on systems-level data

BACKGROUND: The genome-wide identification of both morbid genes, i.e., those genes whose mutations cause hereditary human diseases, and druggable genes, i.e., genes coding for proteins whose modulation by small molecules elicits phenotypic effects, requires experimental approaches that are time-cons...

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Bibliografiske detaljer
Main Authors: Costa, Pedro R, Acencio, Marcio L, Lemke, Ney
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045802/
https://ncbi.nlm.nih.gov/pubmed/21210975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-S5-S9
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