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Natural and Semisynthetic Mammea-Type Isoprenlated Dihydroxycoumarins Uncouple Cellular Respiration

In an effort to identify natural product-based molecular-targeted antitumor agents, mammea-type coumarins from the tropical/subtropical plant Mammea americana were found to inhibit the activation of HIF-1 (hypoxia-inducible factor-1) in human breast and prostate tumor cells. In addition to the recen...

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Bibliografiska uppgifter
Huvudupphovsmän: Du, Lin, Mahdi, Fakhri, Jekabsons, Mika B., Nagle, Dale G., Zhou, Yu-Dong
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045645/
https://ncbi.nlm.nih.gov/pubmed/21214226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np100762s
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