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GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damage
Chromatin structure is known to be a barrier to DNA repair and a large number of studies have now identified various factors that modify histones and remodel nucleosomes to facilitate repair. In response to ultraviolet (UV) radiation several histones are acetylated and this enhances the repair of DN...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045616/ https://ncbi.nlm.nih.gov/pubmed/20972224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq983 |
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