Gliadin-Mediated Proliferation and Innate Immune Activation in Celiac Disease Are Due to Alterations in Vesicular Trafficking

BACKGROUND AND OBJECTIVES: Damage to intestinal mucosa in celiac disease (CD) is mediated both by inflammation due to adaptive and innate immune responses, with IL-15 as a major mediator of the innate immune response, and by proliferation of crypt enterocytes as an early alteration of CD mucosa caus...

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Bibliographische Detailangaben
Hauptverfasser: Barone, M. Vittoria, Zanzi, Delia, Maglio, Mariantonia, Nanayakkara, Merlin, Santagata, Sara, Lania, Giuliana, Miele, Erasmo, Ribecco, Maria Teresa Silvia, Maurano, Francesco, Auricchio, Renata, Gianfrani, Carmen, Ferrini, Silvano, Troncone, Riccardo, Auricchio, Salvatore
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045409/
https://ncbi.nlm.nih.gov/pubmed/21364874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017039
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