In-vivo generation of bone via endochondral ossification by in-vitro chondrogenic priming of adult human and rat mesenchymal stem cells

BACKGROUND: Bone grafts are required to repair large bone defects after tumour resection or large trauma. The availability of patients' own bone tissue that can be used for these procedures is limited. Thus far bone tissue engineering has not lead to an implant which could be used as alternativ...

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Hauptverfasser: Farrell, Eric, Both, Sanne K, Odörfer, Kathrin I, Koevoet, Wendy, Kops, Nicole, O'Brien, Fergal J, de Jong, Robert J Baatenburg, Verhaar, Jan A, Cuijpers, Vincent, Jansen, John, Erben, Reinhold G, van Osch, Gerjo JVM
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045394/
https://ncbi.nlm.nih.gov/pubmed/21281488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-12-31
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