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Tumor Suppressor RASSF1A Promoter: p53 Binding and Methylation

Oncogenes and tumor suppressors work in concert to regulate cell growth or death, which is a pair of antagonist factors for regulation of tumorigenesis. Here we show promoter characteristic of tumor suppressor RASSF1A, which revealed a p53 binding site in the distal and a GC-rich region in the proxi...

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Autors principals: Tian, Yihao, Hou, Yu, Zhou, Xiang, Cheng, Hanhua, Zhou, Rongjia
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045384/
https://ncbi.nlm.nih.gov/pubmed/21364923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017017
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