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Behavioral Characterization of a Mouse Model Overexpressing DSCR1/ RCAN1

DSCR1/ RCAN1 is a chromosome 21 gene found to be overexpressed in the brains of Down syndrome (DS) and postulated as a good candidate to contribute to mental disability. However, even though Rcan1 knockout mice have pronounced spatial learning and memory deficits, the possible deleterious effects of...

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Detalhes bibliográficos
Main Authors: Dierssen, Mara, Arqué, Gloria, McDonald, Jerome, Andreu, Nuria, Martínez-Cué, Carmen, Flórez, Jesús, Fillat, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045383/
https://ncbi.nlm.nih.gov/pubmed/21364922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017010
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