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Protonated base pairs explain the ambiguous pairing properties of O6-methylguanine.

The base-pairing interactions of promutagenic O6-methylguanine (O6-MeGua) with cytosine and thymine in deuterated chloroform were investigated by 1H NMR spectroscopy. Nucleosides were derivatized at hydroxyl positions with triisopropylsilyl groups to obtain solubility in nonaqueous solvents and to p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Williams, L D, Shaw, B R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304524/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470757/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.7.1779
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