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Multiple Proton Confinement in the M2 Channel from the Influenza A Virus

The tetrameric M2 protein bundle of the influenza A virus is the proton channel responsible for the acidification of the viral interior, a key step in the infection cycle. Selective proton transport is achieved by successive protonation of the conserved histidine amino acids at position 37. A recent...

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Bibliografiske detaljer
Main Authors: Carnevale, Vincenzo, Fiorin, Giacomo, Levine, Benjamin G., DeGrado, William F., Klein, Michael L.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045207/
https://ncbi.nlm.nih.gov/pubmed/21359105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp107431g
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