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Arrestin-Rhodopsin Binding Stoichiometry in Isolated Rod Outer Segment Membranes Depends on the Percentage of Activated Receptors

In the rod cell of the retina, arrestin is responsible for blocking signaling of the G-protein-coupled receptor rhodopsin. The general visual signal transduction model implies that arrestin must be able to interact with a single light-activated, phosphorylated rhodopsin molecule (Rho*P), as would be...

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Detalhes bibliográficos
Main Authors: Sommer, Martha E., Hofmann, Klaus Peter, Heck, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044992/
https://ncbi.nlm.nih.gov/pubmed/21169358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.204941
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