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Arrestin-Rhodopsin Binding Stoichiometry in Isolated Rod Outer Segment Membranes Depends on the Percentage of Activated Receptors

In the rod cell of the retina, arrestin is responsible for blocking signaling of the G-protein-coupled receptor rhodopsin. The general visual signal transduction model implies that arrestin must be able to interact with a single light-activated, phosphorylated rhodopsin molecule (Rho*P), as would be...

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Autors principals: Sommer, Martha E., Hofmann, Klaus Peter, Heck, Martin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044992/
https://ncbi.nlm.nih.gov/pubmed/21169358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.204941
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