The Unique Transcriptional Activation Domain of Nuclear Factor-I-X3 Is Critical to Specifically Induce Marker Gene Expression in Astrocytes

Transcription factors of the nuclear factor 1 (NFI) family regulate normal brain development in vertebrates. However, multiple splice variants of four NFI isoforms exist, and their biological functions have yet to be elucidated. Here, we cloned and analyzed human NFI-X3, a novel splice variant of th...

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Detalhes bibliográficos
Main Authors: Singh, Sandeep K., Wilczynska, Katarzyna M., Grzybowski, Adrian, Yester, Jessie, Osrah, Bahiya, Bryan, Lauren, Wright, Sarah, Griswold-Prenner, Irene, Kordula, Tomasz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044988/
https://ncbi.nlm.nih.gov/pubmed/21189253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.152421
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