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S100B Protein Stimulates Microglia Migration via RAGE-dependent Up-regulation of Chemokine Expression and Release

The Ca(2+)-binding protein of the EF-hand type, S100B, is abundantly expressed in and secreted by astrocytes, and release of S100B from damaged astrocytes occurs during the course of acute and chronic brain disorders. Thus, the concept has emerged that S100B might act an unconventional cytokine or a...

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Bibliographic Details
Main Authors: Bianchi, Roberta, Kastrisianaki, Eirini, Giambanco, Ileana, Donato, Rosario
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044978/
https://ncbi.nlm.nih.gov/pubmed/21209080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.169342
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