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S100B Protein Stimulates Microglia Migration via RAGE-dependent Up-regulation of Chemokine Expression and Release

The Ca(2+)-binding protein of the EF-hand type, S100B, is abundantly expressed in and secreted by astrocytes, and release of S100B from damaged astrocytes occurs during the course of acute and chronic brain disorders. Thus, the concept has emerged that S100B might act an unconventional cytokine or a...

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Autors principals: Bianchi, Roberta, Kastrisianaki, Eirini, Giambanco, Ileana, Donato, Rosario
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044978/
https://ncbi.nlm.nih.gov/pubmed/21209080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.169342
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