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A New Cytosolic Pathway from a Parkinson Disease-associated Kinase, BRPK/PINK1: ACTIVATION OF AKT VIA MTORC2
Accumulating evidence indicates that dysfunction of mitochondria is a common feature of Parkinson disease. Functional loss of a familial Parkinson disease-linked gene, BRPK/PINK1 (PINK1), results in deterioration of mitochondrial functions and eventual neuronal cell death. A mitochondrial chaperone...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Biochemistry and Molecular Biology
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3044975/ https://ncbi.nlm.nih.gov/pubmed/21177249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.179390 |
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