Safety and Immunogenicity of an Inactivated Influenza A/H5N1 Vaccine Given with or without Aluminum Hydroxide to Healthy Adults: Results of a Phase I—II Randomized Clinical Trial

BACKGROUND: Dose-sparing strategies are being explored for vaccines against pandemic influenza. We evaluated the dose-sparing potential of aluminum hydroxide (AlOH) adjuvant. METHODS: A total of 600 healthy subjects (age, 18–49 years) were randomized to receive 2 vaccinations 1 month apart with subv...

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Bibliografiska uppgifter
Huvudupphovsmän: Keitel, Wendy A., Campbell, James D., Treanor, John J., Walter, Emmanuel B., Patel, Shital M., He, Fenhua, Noah, Diana L., Hill, Heather
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044935/
https://ncbi.nlm.nih.gov/pubmed/18808338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/592172
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