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Safety and Immunogenicity of an Inactivated Influenza A/H5N1 Vaccine Given with or without Aluminum Hydroxide to Healthy Adults: Results of a Phase I—II Randomized Clinical Trial

BACKGROUND: Dose-sparing strategies are being explored for vaccines against pandemic influenza. We evaluated the dose-sparing potential of aluminum hydroxide (AlOH) adjuvant. METHODS: A total of 600 healthy subjects (age, 18–49 years) were randomized to receive 2 vaccinations 1 month apart with subv...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Keitel, Wendy A., Campbell, James D., Treanor, John J., Walter, Emmanuel B., Patel, Shital M., He, Fenhua, Noah, Diana L., Hill, Heather
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044935/
https://ncbi.nlm.nih.gov/pubmed/18808338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/592172
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