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Modeling a Macrocyclic Bis[Spirodiepoxide] Strategy to Erythronolide A

[Image: see text] A concise route to functionalized 14-membered macrolides related to erythronolide A was achieved. Key steps include the simultaneous formation of bis[allenic] substrates, efficient macrolactonization, highly stereoselective oxidation to the corresponding bis[spirodiepoxide], and nu...

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Detalhes bibliográficos
Main Authors: Ghosh, Partha, Zhang, Yue, Emge, Thomas J., Williams, Lawrence J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044927/
https://ncbi.nlm.nih.gov/pubmed/19725523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol901755a
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