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Tumor-targeted delivery of liposome-encapsulated doxorubicin by use of a peptide that selectively binds to irradiated tumors

Tumor-targeted drug delivery improves anti-tumor efficacy and reduces systemic toxicity by limiting bioavailability of cytotoxic drugs to within tumors. Targeting reagents, such as peptides or antibodies recognizing molecular targets over-expressed within tumors, have been used to improve liposome-e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lowery, Amanda, Onishko, Halina, Hallahan, Dennis E., Han, Zhaozhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044774/
https://ncbi.nlm.nih.gov/pubmed/21075152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.11.006
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