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The Small GTPase RhoA Localizes to the Nucleus and Is Activated by Net1 and DNA Damage Signals

BACKGROUND: Rho GTPases control many cellular processes, including cell survival, gene expression and migration. Rho proteins reside mainly in the cytosol and are targeted to the plasma membrane (PM) upon specific activation by guanine nucleotide exchange factors (GEFs). Accordingly, most GEFs are a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dubash, Adi D., Guilluy, Christophe, Srougi, Melissa C., Boulter, Etienne, Burridge, Keith, García-Mata, Rafael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044755/
https://ncbi.nlm.nih.gov/pubmed/21390328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017380
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