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Bcr is a substrate for Transglutaminase 2 cross-linking activity

BACKGROUND: Breakpoint cluster region (Bcr) is a multi-domain protein that contains a C-terminal GTPase activating protein (GAP) domain for Rac. Transglutaminase 2 (TG2) regulates Bcr by direct binding to its GAP domain. Since TG2 has transglutaminase activity that has been implicated in the respons...

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Bibliografiske detaljer
Main Authors: Yi, Sun-Ju, Groffen, John, Heisterkamp, Nora
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044668/
https://ncbi.nlm.nih.gov/pubmed/21310073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-12-8
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