Mechanism of carboxypeptidase A: hydration of a ketonic substrate analogue.
The structure of the complex between carboxypeptidase A alpha (EC 3.4.17.1) and the ketonic substrate analogue 5-benzamido-2-benzyl-4-oxopentanoic acid (BOP) has been determined by x-ray crystallographic methods to a resolution of 1.7 A (final R = 0.191). Interestingly, BOP was observed to bind to t...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1987
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304464/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470737/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.6.1512 |
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