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Mechanism of carboxypeptidase A: hydration of a ketonic substrate analogue.

The structure of the complex between carboxypeptidase A alpha (EC 3.4.17.1) and the ketonic substrate analogue 5-benzamido-2-benzyl-4-oxopentanoic acid (BOP) has been determined by x-ray crystallographic methods to a resolution of 1.7 A (final R = 0.191). Interestingly, BOP was observed to bind to t...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Christianson, D W, David, P R, Lipscomb, W N
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304464/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470737/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.6.1512
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