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Ensemble and single molecule FRET analysis of the structure and unfolding kinetics of the c-kit promoter quadruplexes

FRET analysis has been used to examine the folded conformations and differing kinetic stabilities of two DNA G-quadruplexes (c-kit 1 and c-kit 2) derived from sequences found in the promoter of the c-kit proto-oncogene.

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Bibliographic Details
Main Authors: Fegan, Adrian, Shirude, Pravin S., Ying, Liming, Balasubramanian, Shankar
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044463/
https://ncbi.nlm.nih.gov/pubmed/20107659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b920680a
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