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Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c-MYC

Single molecule fluorescence spectroscopy has been employed to resolve the conformational heterogeneity, hybridization kinetics and study mutational effects on the c-MYC promoter G-quadruplex.

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Detalles Bibliográficos
Main Authors: Shirude, Pravin S., Ying, Liming, Balasubramanian, Shankar
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426741/
https://ncbi.nlm.nih.gov/pubmed/18536803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b801465e
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