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Geminin promotes neural fate acquisition of embryonic stem cells by maintaining chromatin in an accessible and hyperacetylated state

Formation of the complex vertebrate nervous system begins when pluripotent cells of the early embryo are directed to acquire a neural fate. Although cell intrinsic controls play an important role in this process, the molecular nature of this regulation is not well defined. Here we assessed the role...

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Detalhes bibliográficos
Main Authors: Yellajoshyula, Dhananjay, Patterson, Ethan S., Elitt, Matthew S., Kroll, Kristen L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044367/
https://ncbi.nlm.nih.gov/pubmed/21300881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012053108
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