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Learning probabilistic models of hydrogen bond stability from molecular dynamics simulation trajectories

BACKGROUND: Hydrogen bonds (H-bonds) play a key role in both the formation and stabilization of protein structures. They form and break while a protein deforms, for instance during the transition from a non-functional to a functional state. The intrinsic strength of an individual H-bond has been stu...

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Detalhes bibliográficos
Main Authors: Chikalov, Igor, Yao, Peggy, Moshkov, Mikhail, Latombe, Jean-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044290/
https://ncbi.nlm.nih.gov/pubmed/21342565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S1-S34
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