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Changed epitopes drive the antigenic drift for influenza A (H3N2) viruses

BACKGROUND: In circulating influenza viruses, gradually accumulated mutations on the glycoprotein hemagglutinin (HA), which interacts with infectivity-neutralizing antibodies, lead to the escape of immune system (called antigenic drift). The antibody recognition is highly correlated to the conformat...

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Bibliografski detalji
Glavni autori: Huang, Jhang-Wei, Yang, Jinn-Moon
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044287/
https://ncbi.nlm.nih.gov/pubmed/21342562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S1-S31
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