The HLA Class II Allele DRB1*1501 Is Over-Represented in Patients with Idiopathic Pulmonary Fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive and medically refractory lung disease with a grim prognosis. Although the etiology of IPF remains perplexing, abnormal adaptive immune responses are evident in many afflicted patients. We hypothesized that perturbations of human leukoc...

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Main Authors: Xue, Jianmin, Gochuico, Bernadette R., Alawad, Ahmad Samer, Feghali-Bostwick, Carol A., Noth, Imre, Nathan, Steven D., Rosen, Glenn D., Rosas, Ivan O., Dacic, Sanja, Ocak, Iclal, Fuhrman, Carl R., Cuenco, Karen T., Smith, Mary A., Jacobs, Susan S., Zeevi, Adriana, Morel, Penelope A., Pilewski, Joseph M., Valentine, Vincent G., Gibson, Kevin F., Kaminski, Naftali, Sciurba, Frank C., Zhang, Yingze, Duncan, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044131/
https://ncbi.nlm.nih.gov/pubmed/21373184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014715
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