Poly(ADP-ribose) may signal changing metabolic conditions to the chromatin of mammalian cells.
In mammalian cells, NAD+ serves a dual role as a respiratory coenzyme and as a substrate for the posttranslational poly(ADP-ribose) modification of chromatin proteins, catalyzed by the nuclear enzyme poly(ADP-ribose) polymerase [NAD+ ADP-ribosyltransferase, EC 2.4.2.30]. Biological evidence strongly...
Na minha lista:
| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1987
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3103132/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.5.1286 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|