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The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization

INTRODUCTION: The difficulty in re-growing and mineralizing new bone after severe fracture can result in loss of ambulation or limb. Here we describe the sequential roles of FGF-2 in inducing gene expression, cell growth and BMP-2 in gene expression and mineralization of bone. MATERIALS AND METHODS:...

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Main Authors: Hughes-Fulford, Millie, Li, Chai-Fei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044105/
https://ncbi.nlm.nih.gov/pubmed/21306641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-799X-6-8
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