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FGF and ERK signaling coordinately regulate mineralization-related genes and play essential roles in osteocyte differentiation

To examine the roles of FGF and ERK MAPK signaling in osteocyte differentiation and function, we performed microarray analyses using the osteocyte cell line MLO-Y4. This experiment identified a number of mineralization-related genes that were regulated by FGF2 in an ERK MAPK dependent manner. Real-t...

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Detalhes bibliográficos
Main Authors: Kyono, Ai, Avishai, Nanthawan, Ouyang, Zhufeng, Landreth, Gary E., Murakami, Shunichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192226/
https://ncbi.nlm.nih.gov/pubmed/21678127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00774-011-0288-2
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